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The mission of the Liver Cell Biology in Hepatic Diseases SIG is:

  • To advance and disseminate the science and practice of hepatology, and to promote liver health and quality patient care.

Activity Goals and Objectives

  • Gain a greater understanding of basic cell biological functions of hepatic cells such as protein/lipid traffic, cytoskeletal organization, cellular polarity and receptor signaling cascades in health and disease. Pathological changes in cellular functions can translate into modulation of trafficking, cell adhesion and matrix production leading to liver damage, cholestasis and fibrogenic signals.
  • Understand how the central processes listed above are altered and tailored to suit the highly specialized functions of the liver including regeneration, bile formation, secretion of essential plasma proteins, identification of biomarkers of disease progression and regulation of extracellular matrix turnover.
  • Identify how hepatocellular functions are altered during hepatic diseases such as liver fibrosis and cancer.


Watch the video recording [MP4] from their recent business meeting to learn what their focus will be in 2019.

Communications Subcommittee

  • Chair: VACANT
  • Member: Jessica Maiers, PhD
  • Member: Daniel Antoine, PhD
  • Member: Michele Alves-Bezerra, PhD
  • Member: Harriet Gaskell, BSc, MRes, PhD

Education Subcommittee

  • Co-Chair: Bryon E. Petersen, PhD, FAASLD
  • Co-Chair: Steven A. Weinman, MD, PhD, FAASLD
  • Member: Qisheng Li, MD, PhD
  • Member: Robert E. Schwartz, MD, PhD
  • Member: Z. Gordon Jiang, MD, PhD
  • Member: Sonali J Karnik, PhD

Global Outreach Subcommittee

  • Chair: VACANT
  • Member: Norifumi Kawada, MD, PhD, FAASLD
  • Member: David A. Gerber, MD
  • Member: Aras N. Mattis, MD
  • Member: Yasemin Hatice Balaban, MD
  • Member: Romain Desert, PhD

Membership and Mentorship Subcommittee

  • Chair: Ekihiro Seki, MD, PhD
  • Member: Yuxia Zhang, PhD
  • Member: Kari Nejak-Bowen, MBA, PhD
  • Member: Xiaoyang Zhao, MD, PhD, DIC
  • Member: Davide Povero, PhD

SIG Leadership

  • Yasuko Iwakiri, PhD, FAASLD
  • Natalia Nieto, PhD
  • Carol A. Casey, PhD, FAASLD
  • Udayan Apte, PhD, DABT
    Steering Committee
  • Wen-Xing Ding, MD, PhD, FAASLD
    Steering Committee
  • Petra Hirsova, PharmD, PhD
    Steering Committee
  • Yury Popov, MD, PhD
    Steering Committee
  • Takeshi Saito, MD, PhD
    Steering Committee
  • Steven A. Weinman, MD, PhD, FAASLD
    Steering Committee
  • John Lingerfelt
    Staff Liaison